Drug Information
| Drug General Information | |||||
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| Drug ID |
DX3EIE
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| Drug Name |
7-[(1E)-1-(methoxyimino)-2-methylpropyl]-19-methyl-3,13,19,20-tetraazahexacyclo[14.7.0.0^{2,10}.0^{4,9}.0^{11,15}.0^{17,21}]tricosa-1(16),2(10),4,6,8,11(15),17,20-octaen-14-one
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| Synonyms |
CHEMBL257793
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| Indication | Discovery agent | Investigative | [1587926] | ||
| Formula |
C25H25N5O2
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| Canonical SMILES |
CO\\N=C(/C(C)C)\\c1ccc2[nH]c3c4CCc5nn(C)cc5c4c6C(=O)NCc6c3c2c1
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| InChI |
InChI=1S/C25H25N5O2/c1-12(2)23(29-32-4)13-5-7-18-15(9-13)21-16-10-26-25(31)22(16)20-14(24(21)27-18)6-8-19-17(20)11-30(3)28-19/h5,7,9,11-12,27H,6,8,10H2,1-4H3,(H,26,31)/b29-23+
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| InChIKey |
OKFRLDRBRRTBBF-BYNJWEBRSA-N
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| Target and Pathway | |||||
| Target(s) | Vascular endothelial growth factor receptor 2 | Target Info | [1587926] | ||
| Angiopoietin 1 receptor | Target Info | [1587926] | |||
| NetPath Pathway | IL2 Signaling PathwayNetPath_8:Wnt Signaling Pathway | ||||
| PANTHER Pathway | Angiogenesis | ||||
| VEGF signaling pathwayP00005:Angiogenesis | |||||
| Pathway Interaction Database | HIF-2-alpha transcription factor network | ||||
| Beta3 integrin cell surface interactions | |||||
| Signaling events mediated by TCPTP | |||||
| SHP2 signaling | |||||
| S1P1 pathway | |||||
| VEGF and VEGFR signaling network | |||||
| Integrins in angiogenesis | |||||
| Signaling events mediated by VEGFR1 and VEGFR2 | |||||
| Notch-mediated HES/HEY networkangiopoietinreceptor_pathway:Angiopoietin receptor Tie2-mediated signaling | |||||
| References | |||||
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