Drug Information

Drug General Information
Drug ID
DX2PHP
Drug Name
4-{2-[4-(8-Chloro-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-yl)-piperazin-1-yl]-2-oxo-ethyl}-piperidine-1-carboxylic acid ethylamide
Synonyms
CHEMBL353223
Indication Discovery agent Investigative [1587926]
Formula
C28H36ClN5O2
Canonical SMILES
CCNC(=O)N1CCC(CC(=O)N2CCN(CC2)C3c4ccc(Cl)cc4CCc5cccnc35)CC1
InChI
InChI=1S/C28H36ClN5O2/c1-2-30-28(36)34-12-9-20(10-13-34)18-25(35)32-14-16-33(17-15-32)27-24-8-7-23(29)19-22(24)6-5-21-4-3-11-31-26(21)27/h3-4,7-8,11,19-20,27H,2,5-6,9-10,12-18H2,1H3,(H,30,36)
InChIKey
HJTHHRRMQVGWEY-UHFFFAOYSA-N
Target and Pathway
Target(s) Farnesyltransferase Target Info [1587926]
Protein farnesyltransferase beta subunit Target Info [1587926]
KEGG Pathway Terpenoid backbone biosynthesis
Biosynthesis of antibioticshsa00900:Terpenoid backbone biosynthesis
Biosynthesis of antibiotics
NetPath Pathway TSH Signaling Pathway
Reactome Apoptotic cleavage of cellular proteins
Inactivation, recovery and regulation of the phototransduction cascadeR-HSA-2514859:Inactivation, recovery and regulation of the phototransduction cascade
WikiPathways Visual phototransduction
Apoptotic execution phaseWP2776:Visual phototransduction
References
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017

If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.