Drug Information

Drug General Information
Drug ID
DX2BMW
Drug Name
1-[4-(3-Bromo-8-chloro-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-yl)-piperazin-1-yl]-2-methyl-2-(1-oxy-pyridin-4-yl)-propan-1-one
Synonyms
CHEMBL171785
Indication Discovery agent Investigative [1587926]
Formula
C27H28BrClN4O2
Canonical SMILES
CC(C)(C(=O)N1CCN(CC1)C2c3ccc(Cl)cc3CCc4cc(Br)cnc24)c5cc[n+]([O-])cc5
InChI
InChI=1S/C27H28BrClN4O2/c1-27(2,20-7-9-33(35)10-8-20)26(34)32-13-11-31(12-14-32)25-23-6-5-22(29)16-18(23)3-4-19-15-21(28)17-30-24(19)25/h5-10,15-17,25H,3-4,11-14H2,1-2H3
InChIKey
LIUDLSBEEMADMK-UHFFFAOYSA-N
Target and Pathway
Target(s) Farnesyltransferase Target Info [1587926]
Protein farnesyltransferase beta subunit Target Info [1587926]
KEGG Pathway Terpenoid backbone biosynthesis
Biosynthesis of antibioticshsa00900:Terpenoid backbone biosynthesis
Biosynthesis of antibiotics
NetPath Pathway TSH Signaling Pathway
Reactome Apoptotic cleavage of cellular proteins
Inactivation, recovery and regulation of the phototransduction cascadeR-HSA-2514859:Inactivation, recovery and regulation of the phototransduction cascade
WikiPathways Visual phototransduction
Apoptotic execution phaseWP2776:Visual phototransduction
References
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017

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