Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
DX1VWL
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| Drug Name |
N-((S)-4-methyl-1-((4S,7R)-7-methyl-3-oxo-1-picolinoylazepan-4-ylamino)-1-oxopentan-2-yl)furan-2-carboxamide
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| Synonyms |
CHEMBL1807704
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| Indication | Discovery agent | Investigative | [1587926] | ||
| Formula |
C24H30N4O5
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| Canonical SMILES |
CC(C)C[C@H](NC(=O)c1occc1)C(=O)N[C@H]2CC[C@@H](C)N(CC2=O)C(=O)c3ccccn3
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| InChI |
InChI=1S/C24H30N4O5/c1-15(2)13-19(27-23(31)21-8-6-12-33-21)22(30)26-17-10-9-16(3)28(14-20(17)29)24(32)18-7-4-5-11-25-18/h4-8,11-12,15-17,19H,9-10,13-14H2,1-3H3,(H,26,30)(H,27,31)/t16-,17+,19+/m1/s1
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| InChIKey |
ZLPJZJIBBLLPIY-AOIWGVFYSA-N
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| Target and Pathway | |||||
| Target(s) | Cathepsin K | Target Info | [1587926] | ||
| Cathepsin L | Target Info | [1587926] | |||
| Reactome | Collagen degradation | ||||
| Degradation of the extracellular matrix | |||||
| Activation of Matrix Metalloproteinases | |||||
| Trafficking and processing of endosomal TLR | |||||
| MHC class II antigen presentationR-HSA-1236977:Endosomal/Vacuolar pathway | |||||
| Assembly of collagen fibrils and other multimeric structures | |||||
| MHC class II antigen presentation | |||||
| References | |||||
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