Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
DX1VT1
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| Drug Name |
[1-((3S,4S)-2-Oxo-4-phenoxy-azetidin-3-ylcarbamoyl)-cyclohexyl]-carbamic acid benzyl ester
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| Synonyms |
CHEMBL64612
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| Indication | Discovery agent | Investigative | [1587926] | ||
| Formula |
C24H27N3O5
|
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| Canonical SMILES |
O=C(NC1(CCCCC1)C(=O)N[C@H]2[C@@H](NC2=O)Oc3ccccc3)OCc4ccccc4
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| InChI |
InChI=1S/C24H27N3O5/c28-20-19(21(26-20)32-18-12-6-2-7-13-18)25-22(29)24(14-8-3-9-15-24)27-23(30)31-16-17-10-4-1-5-11-17/h1-2,4-7,10-13,19,21H,3,8-9,14-16H2,(H,25,29)(H,26,28)(H,27,30)/t19-,21+/m1/s1
|
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| InChIKey |
AOOLAAKZAJVJMI-CTNGQTDRSA-N
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| Target and Pathway | |||||
| Target(s) | Cathepsin K | Target Info | [1587926] | ||
| Cathepsin L | Target Info | [1587926] | |||
| Reactome | Collagen degradation | ||||
| Degradation of the extracellular matrix | |||||
| Activation of Matrix Metalloproteinases | |||||
| Trafficking and processing of endosomal TLR | |||||
| MHC class II antigen presentationR-HSA-1236977:Endosomal/Vacuolar pathway | |||||
| Assembly of collagen fibrils and other multimeric structures | |||||
| MHC class II antigen presentation | |||||
| References | |||||
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