Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
DX1JS0
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| Drug Name |
(S)-N-(3-(3-chlorophenyl)-1-(cyanomethylamino)-1-oxopropan-2-yl)-1-naphthamide
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| Synonyms |
CHEMBL551121
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| Indication | Discovery agent | Investigative | [1587926] | ||
| Formula |
C22H18ClN3O2
|
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| Canonical SMILES |
Clc1cccc(C[C@H](NC(=O)c2cccc3ccccc23)C(=O)NCC#N)c1
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| InChI |
InChI=1S/C22H18ClN3O2/c23-17-8-3-5-15(13-17)14-20(22(28)25-12-11-24)26-21(27)19-10-4-7-16-6-1-2-9-18(16)19/h1-10,13,20H,12,14H2,(H,25,28)(H,26,27)/t20-/m0/s1
|
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| InChIKey |
NZBNSOUKYOEUFA-FQEVSTJZSA-N
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| Target and Pathway | |||||
| Target(s) | Cathepsin L | Target Info | [1587926] | ||
| Cathepsin B | Target Info | [1587926] | |||
| Reactome | Endosomal/Vacuolar pathway | ||||
| Collagen degradation | |||||
| Degradation of the extracellular matrix | |||||
| Trafficking and processing of endosomal TLR | |||||
| Assembly of collagen fibrils and other multimeric structures | |||||
| MHC class II antigen presentationR-HSA-1442490:Collagen degradation | |||||
| MHC class II antigen presentation | |||||
| WikiPathways | Primary Focal Segmental Glomerulosclerosis FSGS | ||||
| References | |||||
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