Drug Information

Drug General Information
Drug ID
DX1DXM
Drug Name
(R)-2-Amino-1-(4-{2-[4-(3-bromo-8-chloro-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-yl)-piperazin-1-yl]-2-oxo-ethyl}-piperidin-1-yl)-3-mercapto-propan-1-one
Synonyms
CHEMBL355101
Indication Discovery agent Investigative [1587926]
Formula
C28H35BrClN5O2S
Canonical SMILES
N[C@@H](CS)C(=O)N1CCC(CC(=O)N2CCN(CC2)C3c4ccc(Cl)cc4CCc5cc(Br)cnc35)CC1
InChI
InChI=1S/C28H35BrClN5O2S/c29-21-14-20-2-1-19-15-22(30)3-4-23(19)27(26(20)32-16-21)34-11-9-33(10-12-34)25(36)13-18-5-7-35(8-6-18)28(37)24(31)17-38/h3-4,14-16,18,24,27,38H,1-2,5-13,17,31H2/t24-,27?/m0/s1
InChIKey
WQNXXZXCTCEEJF-BXXZMZEQSA-N
Target and Pathway
Target(s) Farnesyltransferase Target Info [1587926]
Protein farnesyltransferase beta subunit Target Info [1587926]
KEGG Pathway Terpenoid backbone biosynthesis
Biosynthesis of antibioticshsa00900:Terpenoid backbone biosynthesis
Biosynthesis of antibiotics
NetPath Pathway TSH Signaling Pathway
Reactome Apoptotic cleavage of cellular proteins
Inactivation, recovery and regulation of the phototransduction cascadeR-HSA-2514859:Inactivation, recovery and regulation of the phototransduction cascade
WikiPathways Visual phototransduction
Apoptotic execution phaseWP2776:Visual phototransduction
References
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017

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