Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
DX1AU9
|
||||
| Drug Name |
4'-Iodo-biphenyl-4-carboxylic acid {1-[(S)-1-(2-diazo-acetyl)-butylcarbamoyl]-3-methyl-butyl}-amide
|
||||
| Synonyms |
CHEMBL518284
|
||||
| Indication | Discovery agent | Investigative | [1587926] | ||
| Formula |
C25H29IN4O3
|
||||
| Canonical SMILES |
CCC[C@H](NC(=O)C(CC(C)C)NC(=O)c1ccc(cc1)c2ccc(I)cc2)C(=O)C=[N+]=[N-]
|
||||
| InChI |
InChI=1S/C25H29IN4O3/c1-4-5-21(23(31)15-28-27)29-25(33)22(14-16(2)3)30-24(32)19-8-6-17(7-9-19)18-10-12-20(26)13-11-18/h6-13,15-16,21-22H,4-5,14H2,1-3H3,(H,29,33)(H,30,32)/t21-,22?/m0/s1
|
||||
| InChIKey |
VHNVOAVIDBRLFO-HMTLIYDFSA-N
|
||||
| Target and Pathway | |||||
| Target(s) | Cathepsin L | Target Info | [1587926] | ||
| Cathepsin B | Target Info | [1587926] | |||
| Reactome | Endosomal/Vacuolar pathway | ||||
| Collagen degradation | |||||
| Degradation of the extracellular matrix | |||||
| Trafficking and processing of endosomal TLR | |||||
| Assembly of collagen fibrils and other multimeric structures | |||||
| MHC class II antigen presentationR-HSA-1442490:Collagen degradation | |||||
| MHC class II antigen presentation | |||||
| WikiPathways | Primary Focal Segmental Glomerulosclerosis FSGS | ||||
| References | |||||
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.