Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
DX0MNR
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| Drug Name |
(S)-N-[(R)-1-Formyl-2-(1H-indol-3-yl)-ethyl]-2-(naphthalene-1-sulfonylamino)-propionamide
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| Synonyms |
CHEMBL342189
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| Indication | Discovery agent | Investigative | [1587926] | ||
| Formula |
C24H23N3O4S
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| Canonical SMILES |
C[C@H](NS(=O)(=O)c1cccc2ccccc12)C(=O)N[C@H](Cc3c[nH]c4ccccc34)C=O
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| InChI |
InChI=1S/C24H23N3O4S/c1-16(27-32(30,31)23-12-6-8-17-7-2-3-10-21(17)23)24(29)26-19(15-28)13-18-14-25-22-11-5-4-9-20(18)22/h2-12,14-16,19,25,27H,13H2,1H3,(H,26,29)/t16-,19+/m0/s1
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| InChIKey |
UNLVZLHANKRKSG-QFBILLFUSA-N
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| Target and Pathway | |||||
| Target(s) | Cathepsin L | Target Info | [1587926] | ||
| Cathepsin B | Target Info | [1587926] | |||
| Reactome | Endosomal/Vacuolar pathway | ||||
| Collagen degradation | |||||
| Degradation of the extracellular matrix | |||||
| Trafficking and processing of endosomal TLR | |||||
| Assembly of collagen fibrils and other multimeric structures | |||||
| MHC class II antigen presentationR-HSA-1442490:Collagen degradation | |||||
| MHC class II antigen presentation | |||||
| WikiPathways | Primary Focal Segmental Glomerulosclerosis FSGS | ||||
| References | |||||
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