Drug Information

Drug General Information
Drug ID
DX0KYY
Drug Name
4-(3-Bromo-8-chloro-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-yl)-1-(2-pyridin-4-yl-acetyl)-piperazine-2-carboxylic acid cyclopropylmethyl-amide
Synonyms
CHEMBL425032
Indication Discovery agent Investigative [1587926]
Formula
C30H31BrClN5O2
Canonical SMILES
Clc1ccc2C(N3CCN(C(C3)C(=O)NCC4CC4)C(=O)Cc5ccncc5)c6ncc(Br)cc6CCc2c1
InChI
InChI=1S/C30H31BrClN5O2/c31-23-14-22-4-3-21-15-24(32)5-6-25(21)29(28(22)34-17-23)36-11-12-37(27(38)13-19-7-9-33-10-8-19)26(18-36)30(39)35-16-20-1-2-20/h5-10,14-15,17,20,26,29H,1-4,11-13,16,18H2,(H,35,39)
InChIKey
KGSICNXNFOBMJP-UHFFFAOYSA-N
Target and Pathway
Target(s) Farnesyltransferase Target Info [1587926]
Protein farnesyltransferase beta subunit Target Info [1587926]
KEGG Pathway Terpenoid backbone biosynthesis
Biosynthesis of antibioticshsa00900:Terpenoid backbone biosynthesis
Biosynthesis of antibiotics
NetPath Pathway TSH Signaling Pathway
Reactome Apoptotic cleavage of cellular proteins
Inactivation, recovery and regulation of the phototransduction cascadeR-HSA-2514859:Inactivation, recovery and regulation of the phototransduction cascade
WikiPathways Visual phototransduction
Apoptotic execution phaseWP2776:Visual phototransduction
References
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017

If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.