Drug Information
Drug General Information | |||||
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Drug ID |
D00ELE
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Former ID |
DIB011242
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Drug Name |
XL-647
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Synonyms |
Renal system agent (polycystic kidney disease), Primrose; XL-647, Primrose
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Drug Type |
Small molecular drug
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Company |
Primrose Therapeutics Inc
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Structure |
Download2D MOL |
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Formula |
C24H25Cl2FN4O2
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InChI |
InChI=1S/C24H25Cl2FN4O2/c1-31-9-14-5-13(6-15(14)10-31)11-33-21-8-19-16(7-20(21)32-2)24(29-12-28-19)30-18-4-3-17(25)22(26)23(18)27/h3-4,7-8,12-15H,5-6,9-11H2,1-2H3,(H,28,29,30)/t13?,14-,15+
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InChIKey |
HVXKQKFEHMGHSL-GOOCMWNKSA-N
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PubChem Compound ID | |||||
PubChem Substance ID |
15480187, 22792072, 40585946, 76905083, 127347070, 135378337, 136340286, 136345873, 137747606, 137747791, 162011572, 162038219, 162109071, 163818983, 163819000, 164042005, 172919892, 184811990, 198983317, 223400036, 227010733, 227010734, 227010735, 243284522, 243309177, 249565627, 252225708, 252473918
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Drug Resistance Mutation (DRM) | |||||
DRM | DRM Info | ||||
References | |||||
Ref 521873 | ClinicalTrials.gov (NCT00364780) Study of XL647 in Subjects With Non-Small-Cell Lung Cancer. U.S. National Institutes of Health. | ||||
Ref 542859 | (http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 7944). |
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