Drug General Information
Drug ID
D00ELE
Former ID
DIB011242
Drug Name
XL-647
Synonyms
Renal system agent (polycystic kidney disease), Primrose; XL-647, Primrose
Drug Type
Small molecular drug
Indication Polycystic kidney disease [ICD9: 753.1; ICD10:Q61] Phase 2 [521873], [542859]
Company
Primrose Therapeutics Inc
Structure
Download
2D MOL
Formula
C24H25Cl2FN4O2
InChI
InChI=1S/C24H25Cl2FN4O2/c1-31-9-14-5-13(6-15(14)10-31)11-33-21-8-19-16(7-20(21)32-2)24(29-12-28-19)30-18-4-3-17(25)22(26)23(18)27/h3-4,7-8,12-15H,5-6,9-11H2,1-2H3,(H,28,29,30)/t13?,14-,15+
InChIKey
HVXKQKFEHMGHSL-GOOCMWNKSA-N
PubChem Compound ID
PubChem Substance ID
Drug Resistance Mutation (DRM)
DRM DRM Info
References
Ref 521873ClinicalTrials.gov (NCT00364780) Study of XL647 in Subjects With Non-Small-Cell Lung Cancer. U.S. National Institutes of Health.
Ref 542859(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 7944).

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