Resistance mutation info of target
Target General Information | ||||||||||||||||||
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Target ID | T83793 | |||||||||||||||||
Target Name | HIV Negative factor (nef) | |||||||||||||||||
Gene Name | nef | |||||||||||||||||
Species | Human immunodeficiency virus type 1 (HIV-1) | |||||||||||||||||
UniProt ID | NEF_HV1A2 | |||||||||||||||||
Sequence |
MGGKWSKRSMGGWSAIRERMRRAEPRAEPAADGVGAVSRDLEKHGAITSSNTAATNADCA WLEAQEEEEVGFPVRPQVPLRPMTYKAALDISHFLKEKGGLEGLIWSQRRQEILDLWIYH TQGYFPDWQNYTPGPGIRYPLTFGWCFKLVPVEPEKVEEANEGENNSLLHPMSLHGMEDA EKEVLVWRFDSKLAFHHMARELHPEYYKDC [Human immunodeficiency virus type 1 (HIV-1)] |
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Drug and Corresponding Resistance Mutations | ||||||||||||||||||
Mutation Info | Missense: D174N | |||||||||||||||||
Drugs |
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References | ||||||||||||||||||
REF 1 | Inhibition of human immunodeficiency virus type 1 by triciribine involves the accessory protein nef.Antimicrob Agents Chemother.2010 Apr;54(4):1512-9. |
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