Resistance mutation info of target
Target General Information | ||||||||||||||||||
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Target ID | T53489 | |||||||||||||||||
Target Name | Parasitic Cytochrome b (MT-CYB) | |||||||||||||||||
Gene Name | MT-CYB | |||||||||||||||||
Species | Plasmodium falciparum | |||||||||||||||||
UniProt ID | CYB_PLAFA | |||||||||||||||||
Sequence |
MNFYSINLVKAHLINYPCPLNINFLWNYGFLLGIIFFIQIITGVFLASRYTPDVSYAYYS IQHILRELWSGWCFRYMHATGASLVFLLTYLHILRGLNYSYMYLPLSWISGLILFMIFIV TAFVGYVLPWGQMSYWGATVITNLLSSIPVAVIWICGGYTVSDPTIKRFFVLHFILPFIG LCIVFIHIFFLHLHGSTNPLGYDTALKIPFYPNLLSLDVKGFNNVIILFLIQSLFGIIPL SHPDNAIVVNTYVTPSQIVPEWYFLPFYAMLKTVPSKPAGLVIVLLSLQLLFLLAEQRSL TTIIQFKMIFGARDYSVPIIWFMCAFYALLWIGCQLPQDIFILYGRLFIVLFFCSGLFVL VHYRRTHYDYSSQANI [Plasmodium falciparum] |
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Drug and Corresponding Resistance Mutations | ||||||||||||||||||
Mutation Info | Missense: Y268S | |||||||||||||||||
Drugs |
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References | ||||||||||||||||||
REF 1 | Understanding the mechanism of atovaquone drug resistance in Plasmodium falciparum cytochrome b mutation Y268S using computational methods. PLoS One. 2014 Oct 15;9(10):e110041. |
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