Target Information
| Target General Information | Top | |||||
|---|---|---|---|---|---|---|
| Target ID |
T99935
(Former ID: TTDI01589)
|
|||||
| Target Name |
GPCR unspecific (GPCR)
|
|||||
| Gene Name |
NO-GeName
|
|||||
| Target Type |
Discontinued target
|
[1] | ||||
| Disease | [+] 6 Target-related Diseases | + | ||||
| 1 | Sexual dysfunction [ICD-11: HA00-HA01] | |||||
| 2 | Depression [ICD-11: 6A70-6A7Z] | |||||
| 3 | Nausea/vomiting [ICD-11: MD90] | |||||
| 4 | Alzheimer disease [ICD-11: 8A20] | |||||
| 5 | Functional bladder disorder [ICD-11: GC50] | |||||
| 6 | Prostate hyperplasia [ICD-11: GA90] | |||||
| UniProt ID | ||||||
| Drugs and Modes of Action | Top | |||||
|---|---|---|---|---|---|---|
| Discontinued Drug(s) | [+] 7 Discontinued Drugs | + | ||||
| 1 | R-873 | Drug Info | Discontinued in Phase 2 | Erectile dysfunction | [2] | |
| 2 | R-1068 | Drug Info | Discontinued in Phase 1 | Vomiting | [3] | |
| 3 | R-701 | Drug Info | Discontinued in Phase 1 | Overactive bladder | [4] | |
| 4 | R1204 | Drug Info | Discontinued in Phase 1 | Depression | [5] | |
| 5 | R-1315 | Drug Info | Terminated | Alzheimer disease | [6] | |
| 6 | R-1437 | Drug Info | Terminated | Prostate hyperplasia | [7] | |
| 7 | R-1554 | Drug Info | Terminated | Overactive bladder | [8] | |
| Mode of Action | [+] 3 Modes of Action | + | ||||
| Agonist | [+] 1 Agonist drugs | + | ||||
| 1 | R-873 | Drug Info | [1] | |||
| Modulator | [+] 3 Modulator drugs | + | ||||
| 1 | R-1068 | Drug Info | [9] | |||
| 2 | R1204 | Drug Info | [11] | |||
| 3 | R-1315 | Drug Info | [12] | |||
| Antagonist | [+] 3 Antagonist drugs | + | ||||
| 1 | R-701 | Drug Info | [10] | |||
| 2 | R-1437 | Drug Info | [13] | |||
| 3 | R-1554 | Drug Info | [14] | |||
| References | Top | |||||
|---|---|---|---|---|---|---|
| REF 1 | Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800020830) | |||||
| REF 2 | Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800020830) | |||||
| REF 3 | Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800018362) | |||||
| REF 4 | Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800017119) | |||||
| REF 5 | Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800017253) | |||||
| REF 6 | Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800017252) | |||||
| REF 7 | Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800017122) | |||||
| REF 8 | Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800018539) | |||||
| REF 9 | R 1068 Roche discontinued, Europe (emesis). R & D Focus Drug New. February 16, 2004 | |||||
| REF 10 | R 701 Roche discontinued, USA (overactive bladder), R & D Focus Drug News. February 23, 2004 | |||||
| REF 11 | Clinical pipeline report, company report or official report of Roche. | |||||
| REF 12 | Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800017252) | |||||
| REF 13 | Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800017122) | |||||
| REF 14 | Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800018539) | |||||
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