Target Information
| Target General Information | Top | |||||
|---|---|---|---|---|---|---|
| Target ID |
T88483
|
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| Target Name |
microRNA hsa-miR-155 (MIR155)
|
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| Gene Name |
NO-GeName
|
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| Target Type |
Clinical trial target
|
[1] | ||||
| Disease | [+] 5 Target-related Diseases | + | ||||
| 1 | Keloid/hypertrophic scar [ICD-11: EE60] | |||||
| 2 | Mycosis fungoides [ICD-11: 2B01] | |||||
| 3 | Diffuse large B-cell lymphoma [ICD-11: 2A81] | |||||
| 4 | Mature B-cell leukaemia [ICD-11: 2A82] | |||||
| 5 | Systemic sclerosis [ICD-11: 4A42] | |||||
| BioChemical Class |
Non-coding RNA target
|
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| UniProt ID | ||||||
| Drugs and Modes of Action | Top | |||||
|---|---|---|---|---|---|---|
| Clinical Trial Drug(s) | [+] 2 Clinical Trial Drugs | + | ||||
| 1 | Cobomarsen | Drug Info | Phase 2 | Cutaneous T-cell lymphoma | [2] | |
| 2 | MRG-201 | Drug Info | Phase 2 | Keloid | [3] | |
| Mode of Action | [+] 2 Modes of Action | + | ||||
| Inhibitor | [+] 1 Inhibitor drugs | + | ||||
| 1 | Cobomarsen | Drug Info | [1], [4] | |||
| Modulator | [+] 1 Modulator drugs | + | ||||
| 1 | MRG-201 | Drug Info | [5] | |||
| References | Top | |||||
|---|---|---|---|---|---|---|
| REF 1 | Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA) | |||||
| REF 2 | ClinicalTrials.gov (NCT03837457) PRISM: Efficacy and Safety of Cobomarsen (MRG-106) in Subjects With Mycosis Fungoides Who Have Completed the SOLAR Study (PRISM). U.S. National Institutes of Health. | |||||
| REF 3 | ClinicalTrials.gov (NCT03601052) Efficacy, Safety, and Tolerability of Remlarsen (MRG-201) Following Intradermal Injection in Subjects With a History of Keloids. U.S. National Institutes of Health. | |||||
| REF 4 | Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA) | |||||
| REF 5 | Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA) | |||||
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