Target Information
| Target General Information | Top | |||||
|---|---|---|---|---|---|---|
| Target ID |
T72915
|
|||||
| Target Name |
Casein kinase 1 (CK1)
|
|||||
| Gene Name |
NO-GeName
|
|||||
| Target Type |
Preclinical target
|
[1] | ||||
| Disease | [+] 1 Target-related Diseases | + | ||||
| 1 | Mood disorder [ICD-11: 6A60-6E23] | |||||
| UniProt ID | ||||||
| Drugs and Modes of Action | Top | |||||
|---|---|---|---|---|---|---|
| Preclinical Drug(s) | [+] 2 Preclinical Drugs | + | ||||
| 1 | CKI-7 | Drug Info | Preclinical | Mood disorder | [2] | |
| 2 | LH846 | Drug Info | Preclinical | Mood disorder | [2] | |
| Mode of Action | [+] 1 Modes of Action | + | ||||
| Inhibitor | [+] 2 Inhibitor drugs | + | ||||
| 1 | CKI-7 | Drug Info | [1] | |||
| 2 | LH846 | Drug Info | [3] | |||
| References | Top | |||||
|---|---|---|---|---|---|---|
| REF 1 | Crystal structures of two aminoglycoside kinases bound with a eukaryotic protein kinase inhibitor. PLoS One. 2011 May 9;6(5):e19589. | |||||
| REF 2 | Circadian rhythm as a therapeutic target. Nat Rev Drug Discov. 2021 Apr;20(4):287-307. | |||||
| REF 3 | A small molecule modulates circadian rhythms through phosphorylation of the period protein. Angew Chem Int Ed Engl. 2011 Nov 4;50(45):10608-11. | |||||
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