Target Information
| Target General Information | Top | |||||
|---|---|---|---|---|---|---|
| Target ID |
T52258
(Former ID: TTDI01242)
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| Target Name |
Hepatitis B virus messenger RNA (HBV mRNA)
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| Synonyms |
mRNA of HBV protein
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| Gene Name |
NO-GeName
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| Target Type |
Clinical trial target
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[1] | ||||
| Disease | [+] 1 Target-related Diseases | + | ||||
| 1 | Hepatitis virus infection [ICD-11: 1E50-1E51] | |||||
| BioChemical Class |
mRNA target
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| UniProt ID | ||||||
| Drugs and Modes of Action | Top | |||||
|---|---|---|---|---|---|---|
| Clinical Trial Drug(s) | [+] 3 Clinical Trial Drugs | + | ||||
| 1 | AB-729 | Drug Info | Phase 2 | Hepatitis B virus infection | [2] | |
| 2 | ISIS-HBV | Drug Info | Phase 2 | Hepatitis B virus infection | [3] | |
| 3 | ARO-HBV | Drug Info | Phase 1/2 | Hepatitis B | [4] | |
| Mode of Action | [+] 1 Modes of Action | + | ||||
| Inhibitor | [+] 2 Inhibitor drugs | + | ||||
| 1 | AB-729 | Drug Info | [5] | |||
| 2 | ARO-HBV | Drug Info | [6] | |||
| References | Top | |||||
|---|---|---|---|---|---|---|
| REF 1 | Clinical pipeline report, company report or official report of ISIS Pharmaceuticals. | |||||
| REF 2 | ClinicalTrials.gov (NCT04820686) A Study Evaluating Treatment Regimens Containing Vebicorvir (ABI-H0731) in Participants With Chronic Hepatitis B Infection. U.S. National Institutes of Health. | |||||
| REF 3 | Clinical pipeline report, company report or official report of ISIS Pharmaceuticals. | |||||
| REF 4 | ClinicalTrials.gov (NCT03365947) Study of ARO-HBV in Normal Adult Volunteers and Patients With Hepatitis B Virus (HBV). U.S. National Institutes of Health. | |||||
| REF 5 | Clinical pipeline report, company report or official report of Arbutus Biopharma. | |||||
| REF 6 | Clinical pipeline report, company report or official report of Arrowhead Pharmaceuticals. | |||||
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