Target Information
Target General Information | Top | |||||
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Target ID |
T21617
(Former ID: TTDI01551)
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Target Name |
Signal transduction unspecific (ST)
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Gene Name |
NO-GeName
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Target Type |
Clinical trial target
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[1] | ||||
Disease | [+] 1 Target-related Diseases | + | ||||
1 | Lupus erythematosus [ICD-11: 4A40] | |||||
UniProt ID |
Drugs and Modes of Action | Top | |||||
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Clinical Trial Drug(s) | [+] 2 Clinical Trial Drugs | + | ||||
1 | Forigerimod | Drug Info | Phase 3 | Systemic lupus erythematosus | [2] | |
2 | OMN-54 | Drug Info | Phase 1 | Solid tumour/cancer | [3] | |
Mode of Action | [+] 2 Modes of Action | + | ||||
Modulator | [+] 1 Modulator drugs | + | ||||
1 | Forigerimod | Drug Info | [4], [5] | |||
Inhibitor | [+] 1 Inhibitor drugs | + | ||||
1 | OMN-54 | Drug Info | [1] |
References | Top | |||||
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REF 1 | Enhanced anticancer activity of a combination of docetaxel and Aneustat (OMN54) in a patient-derived, advanced prostate cancer tissue xenograft model. Mol Oncol. 2014 Mar;8(2):311-22. | |||||
REF 2 | ClinicalTrials.gov (NCT01240694) A Long-Term Study of the Safety and Tolerability of Repeated Administration of CEP-33457 in Patients With Systemic Lupus Erythematosus. U.S. National Institutes of Health. | |||||
REF 3 | ClinicalTrials.gov (NCT01555242) A Study of Aneustat (OMN54) in Patients With Advanced Cancer and Lymphomas. U.S. National Institutes of Health. | |||||
REF 4 | Spliceosomal peptide P140 for immunotherapy of systemic lupus erythematosus: results of an early phase II clinical trial. Arthritis Rheum. 2008 Dec;58(12):3873-83. | |||||
REF 5 | Clinical pipeline report, company report or official report of ImmuPharma. |
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