| Target Validation Information | |||||
|---|---|---|---|---|---|
| TTD ID | T94309 | ||||
| Target Name | Pancreatic triacylglycerol lipase (PNLIP) | ||||
| Type of Target |
Successful |
||||
| Drug Potency against Target | Dalbavancin | Drug Info | MIC50 = 0.06 ug/ml | [1] | |
| Action against Disease Model | Dalbavancin | Drug Info | In a recent survey of more than 1100 MRSA clinical isolates, the MIC50 of dalbavancin was 0.06 mg/L, compared with 1 and 0.5 mg/L, respectively, for vancomycin and teicoplanin. | [2] | |
| References | |||||
| REF 1 | Novel antibacterial agents for the treatment of serious Gram-positive infections. Expert Opin Investig Drugs. 2003 Mar;12(3):379-99. | ||||
| REF 2 | Effects of age on parathyroid hormone signaling in human marrow stromal cells. Aging Cell. 2011 Oct;10(5):780-8. | ||||
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.