| Target Validation Information | |||||
|---|---|---|---|---|---|
| TTD ID | T88452 | ||||
| Target Name | Corticosteroid-binding globulin (SERPINA6) | ||||
| Type of Target |
Successful |
||||
| Drug Potency against Target | Ciclesonide | Drug Info | IC50 = 210 nM | [1] | |
| Action against Disease Model | Triamcinolone | Drug Info | Type II corticosterold receptors measured in whole C6 glioma cells IC50: 2.5 nM | ||
| References | |||||
| REF 1 | Preclinical profile of ciclesonide, a novel corticosteroid for the treatment of asthma. J Pharmacol Exp Ther. 2005 Aug;314(2):568-74. | ||||
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.