Target Validation Information | |||||
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TTD ID | T87875 | ||||
Target Name | Glucagon receptor messenger RNA (GCGR mRNA) | ||||
Type of Target |
Clinical trial |
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Action against Disease Model | ISIS 325568 | Drug Info | ISIS 325568, is a second generation antisense drug that inhibits the body's ability to produce the excessive amounts of glucose. ISIS 325568 inhibits the expression of GCGR leading to a reduction in the ability of glucagon to produce glucose and cancelling out a lack of sensitivity to insulin. | ||
References | |||||
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