Target Validation Information
TTD ID T87875
Target Name Glucagon receptor messenger RNA (GCGR mRNA)
Type of Target
Clinical trial
Action against Disease Model ISIS 325568 Drug Info ISIS 325568, is a second generation antisense drug that inhibits the body's ability to produce the excessive amounts of glucose. ISIS 325568 inhibits the expression of GCGR leading to a reduction in the ability of glucagon to produce glucose and cancelling out a lack of sensitivity to insulin.
References

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