| Target Validation Information | |||||
|---|---|---|---|---|---|
| TTD ID | T71905 | ||||
| Target Name | Bacterial 16S ribosomal RNA (Bact 16S rRNA) | ||||
| Type of Target |
Successful |
||||
| Action against Disease Model | Drug Info | Minimal inhibitory concentration (MIC) with nine antibiotics was determined on 188 isolates of S. pyogenes collected from outpatients with pharyngitis in four children's hospitals in different regions of China in 2007. MICs of penicillin, chloramphenicol, cefradine, levofloxacin, macrolide (erythromycin, clarithromycin, azithromycin,), clindamycin, and tetracycline were determined by the microdilution method. Over 95% were resistant to macrolides, while 92.0% were resistant to tetracycline. | [1] | ||
| References | |||||
| REF 1 | High macrolide resistance in Streptococcus pyogenes strains isolated from children with pharyngitis in China. Pediatr Pulmonol. 2009 May;44(5):436-41. | ||||
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.