Target Validation Information | |||||
---|---|---|---|---|---|
TTD ID | T70680 | ||||
Target Name | Solute carrier family 22 member 8 (SLC22A8) | ||||
Type of Target |
Successful |
||||
Drug Potency against Target | 3R14S-OCHRATOXIN A | Drug Info | Ki = 6200 nM | [1] | |
ADIPATE | Drug Info | Ki = 410 nM | [1] | ||
AMINOHIPPURIC ACID | Drug Info | Ki = 9400 nM | [1] | ||
FLUORESCEIN | Drug Info | Ki = 3000 nM | [1] | ||
GLUTARATE | Drug Info | Ki = 6700 nM | [1] | ||
HEPTANOATE | Drug Info | Ki = 16700 nM | [1] | ||
References | |||||
REF 1 | Structural variation governs substrate specificity for organic anion transporter (OAT) homologs. Potential remote sensing by OAT family members. J Biol Chem. 2007 Aug 17;282(33):23841-53. | ||||
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