| Target Validation Information | |||||
|---|---|---|---|---|---|
| TTD ID | T55689 | ||||
| Target Name | Hormone sensitive lipase (LIPE) | ||||
| Type of Target |
Successful |
||||
| Drug Potency against Target | NCI-159878 | Drug Info | IC50 = 2980 nM | [1] | |
| NCI-58425 | Drug Info | IC50 = 210 nM | [1] | ||
| OXYBENZONE | Drug Info | IC50 = 3250 nM | [1] | ||
| References | |||||
| REF 1 | Combining ligand-based pharmacophore modeling, quantitative structure-activity relationship analysis and in silico screening for the discovery of n... J Med Chem. 2008 Oct 23;51(20):6478-94. | ||||
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