| Target Validation Information | |||||
|---|---|---|---|---|---|
| TTD ID | T52946 | ||||
| Target Name | Gamma-hydroxybutyrate receptor (SLC52A2) | ||||
| Type of Target |
Literature-reported |
||||
| Drug Potency against Target | 4-Cyclohexyl-4-hydroxy-but-2-enoic acid | Drug Info | IC50 = 3.3 nM | [1] | |
| 4-hydroxy-but-2-enoate | Drug Info | IC50 = 3.5 nM | [1] | ||
| 4-Hydroxy-pent-2-enoic acid | Drug Info | IC50 = 11 nM | [1] | ||
| References | |||||
| REF 1 | Analogues of gamma-hydroxybutyric acid. Synthesis and binding studies. J Med Chem. 1988 May;31(5):893-7. | ||||
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