| Target Validation Information | |||||
|---|---|---|---|---|---|
| TTD ID | T51748 | ||||
| Target Name | HIF1-alpha messenger RNA (HIF1A mRNA) | ||||
| Type of Target |
Clinical trial |
||||
| Drug Potency against Target | (5-(1-benzyl-1H-indazol-3-yl)furan-2-yl)methanol | Drug Info | IC50 = 13800 nM | [1] | |
| References | |||||
| REF 1 | Synthesis of (aryloxyacetylamino)-isonicotinic/nicotinic acid analogues as potent hypoxia-inducible factor (HIF)-1alpha inhibitors. Bioorg Med Chem Lett. 2007 Nov 15;17(22):6305-10. | ||||
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