| Target Validation Information | |||||
|---|---|---|---|---|---|
| TTD ID | T43332 | ||||
| Target Name | Coagulation factor VII (F7) | ||||
| Type of Target |
Successful |
||||
| Drug Potency against Target | 4-(3,4-Diethoxy-benzylamino)-benzamidine | Drug Info | Ki = 4200 nM | [1] | |
| 4-(4-Benzyloxy-3-methoxy-benzylamino)-benzamidine | Drug Info | Ki = 1000 nM | [1] | ||
| References | |||||
| REF 1 | Design of selective phenylglycine amide tissue factor/factor VIIa inhibitors. Bioorg Med Chem Lett. 2005 Feb 1;15(3):817-22. | ||||
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