Target Validation Information | |||||
---|---|---|---|---|---|
TTD ID | T41766 | ||||
Target Name | IRAK4 messenger RNA (IRAK4 mRNA) | ||||
Type of Target |
Literature-reported |
||||
Drug Potency against Target | N-(1H-benzo[d]imidazol-2-yl)-3-cyanobenzamide | Drug Info | IC50 = 13600 nM | [1] | |
N-(1H-benzo[d]imidazol-2-yl)-3-nitrobenzamide | Drug Info | IC50 = 4000 nM | [1] | ||
References | |||||
REF 1 | Discovery and initial SAR of inhibitors of interleukin-1 receptor-associated kinase-4. Bioorg Med Chem Lett. 2006 Jun 1;16(11):2842-5. | ||||
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