Target Validation Information
TTD ID T41766
Target Name IRAK4 messenger RNA (IRAK4 mRNA)
Type of Target
Literature-reported
Drug Potency against Target N-(1H-benzo[d]imidazol-2-yl)-3-cyanobenzamide Drug Info IC50 = 13600 nM [1]
N-(1H-benzo[d]imidazol-2-yl)-3-nitrobenzamide Drug Info IC50 = 4000 nM [1]
References
REF 1 Discovery and initial SAR of inhibitors of interleukin-1 receptor-associated kinase-4. Bioorg Med Chem Lett. 2006 Jun 1;16(11):2842-5.

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