Target Validation Information
TTD ID T34287
Target Name Candida Mannose-6-phosphate isomerase (Candi PMI1)
Type of Target
Successful
Drug Potency against Target GNF-PF-2272 Drug Info IC50 = 6088 nM [1]
GNF-PF-5134 Drug Info IC50 = 13733 nM [1]
NSC-66209 Drug Info IC50 = 3550 nM [1]
References
REF 1 In silico identification and biochemical evaluation of novel inhibitors of NRH:quinone oxidoreductase 2 (NQO2). Bioorg Med Chem Lett. 2010 Dec 15;20(24):7331-6.

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