Target Validation Information | |||||
---|---|---|---|---|---|
TTD ID | T33901 | ||||
Target Name | Niemann-Pick C1-like protein 1 (NPC1L1) | ||||
Type of Target |
Successful |
||||
Drug Potency against Target | Ezetimibe-glucuronide | Drug Info | IC50 = 30 nM | [1] | |
References | |||||
REF 1 | Spiroimidazolidinone NPC1L1 inhibitors. 1: Discovery by 3D-similarity-based virtual screening. Bioorg Med Chem Lett. 2009 Jun 1;19(11):2965-8. | ||||
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