| Target Validation Information | |||||
|---|---|---|---|---|---|
| TTD ID | T30727 | ||||
| Target Name | Caspase-11 (CASP11) | ||||
| Type of Target |
Literature-reported |
||||
| Drug Potency against Target | Grassystatin a | Drug Info | IC50 = 5000 nM | [1] | |
| References | |||||
| REF 1 | Grassystatins A-C from marine cyanobacteria, potent cathepsin E inhibitors that reduce antigen presentation. J Med Chem. 2009 Sep 24;52(18):5732-47. | ||||
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