Target Validation Information
TTD ID	T27944
Target Name	Neuropeptide Y receptor type 4 (NPY4R)
Type of Target	Clinical trial
Drug Potency against Target	Adp[-Trp-Arg-Nva-Arg-Tyr-NH2]2	Drug Info	Ki = 4.2 nM	[1]
	H-[Trp-Arg-Nva-Arg-Tyr]2-NH2	Drug Info	Ki = 5.3 nM	[1]
	H-[Trp-Arg-Nva-Arg-Tyr]3-NH2	Drug Info	Ki = 3.9 nM	[1]
	Pim[-Trp-Arg-Nva-Arg-Tyr-NH2]2	Drug Info	Ki = 4.3 nM	[1]
	Sub[-Trp-Arg-Nva-Arg-Tyr-NH2]2	Drug Info	Ki = 4.1 nM	[1]
	[Cys-Trp-Arg-Nva-Arg-Tyr-NH2]2	Drug Info	Ki = 30 nM	[1]
References
REF 1	Neuropeptide Y (NPY) Y4 receptor selective agonists based on NPY(32-36): development of an anorectic Y4 receptor selective agonist with picomolar a... J Med Chem. 2006 Apr 20;49(8):2661-5.

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