| Target Validation Information | |||||
|---|---|---|---|---|---|
| TTD ID | T24334 | ||||
| Target Name | Bacterial Deoxyuridine triphosphate nucleotidohydrolase (Bact dut) | ||||
| Type of Target |
Literature-reported |
||||
| Drug Potency against Target | 1-(3-tritylaminopropyl)uracil | Drug Info | Ki = 1400 nM | [1] | |
| 1-[(Z)-4-trityloxy-2-butenyl]uracil | Drug Info | Ki = 5200 nM | [1] | ||
| 1-[2-(trityloxy)ethoxymethyl]uracil | Drug Info | Ki = 17000 nM | [1] | ||
| 1-[4-hydroxy-3-(tritylaminomethyl)butyl]uracil | Drug Info | Ki = 5700 nM | [1] | ||
| References | |||||
| REF 1 | Acyclic nucleoside analogues as inhibitors of Plasmodium falciparum dUTPase. J Med Chem. 2006 Jul 13;49(14):4183-95. | ||||
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.