Target Validation Information
TTD ID T13057
Target Name Protein-tyrosine phosphatase SHP-2 (PTPN11)
Type of Target
Clinical trial
Drug Potency against Target Drug Info IC50 = 300 nM [1]
References
REF 1 Inhibitors of Src homology-2 domain containing protein tyrosine phosphatase-2 (Shp2) based on oxindole scaffolds. J Med Chem. 2008 Aug 28;51(16):4948-56.

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