| Target Validation Information | |||||
|---|---|---|---|---|---|
| TTD ID | T12355 | ||||
| Target Name | G1/S-specific cyclin-D1 (CCND1) | ||||
| Type of Target |
Clinical trial |
||||
| Drug Potency against Target | 4-[(3,5-diamino-1H-pyrazol-4-yl)diazenyl]phenol | Drug Info | IC50 = 13500 nM | [1] | |
| References | |||||
| REF 1 | 4-arylazo-3,5-diamino-1H-pyrazole CDK inhibitors: SAR study, crystal structure in complex with CDK2, selectivity, and cellular effects. J Med Chem. 2006 Nov 2;49(22):6500-9. | ||||
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