Target Interacting Protein Information

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Target General Information
Target Interacting Proteins
References
Target General Information  Top
Target ID T99394 Target Info
Target Name Transmembrane activator and CAML interactor (TNFRSF13B)
Synonyms Tumor necrosis factor receptor superfamily member 13B; TACI; CD267
Target Type Clinical trial Target
Gene Name TNFRSF13B
UniProt ID
TR13B_HUMAN 
Target Interacting Proteins  Top
Acyltransferases [+] 2 Acyltransferases +
Interacting Target Name TNF receptor-associated factor 6 (TRAF6) Literature-reported Target Interacting Protein Info
UniProt ID
TRAF6_HUMAN 
Synonyms RNF85; RING-type E3 ubiquitin transferase TRAF6; RING finger protein 85; Interleukin-1 signal transducer; E3 ubiquitin-protein ligase TRAF6
Evidence Score (E-score) 2 Experimental Evidences +
1 Affinity Capture-Western [1]
2 Yeast two hybrid [2]
Interacting Protein Name TNF receptor-associated factor 2 (TRAF2) Interacting Protein Interacting Protein Info
UniProt ID
TRAF2_HUMAN 
Synonyms MGC:45012; TRAP; TRAP3
Evidence Score (E-score) 2 Experimental Evidences +
1 Affinity Capture-Western [1]
2 Yeast two hybrid [2]
Adapter proteins [+] 1 Adapter proteins +
Interacting Protein Name TNF receptor-associated factor 5 (TRAF5) Interacting Protein Interacting Protein Info
UniProt ID
TRAF5_HUMAN 
Synonyms MGC:39780; RNF84
Evidence Score (E-score) 2 Experimental Evidences +
1 Affinity Capture-Western [1]
2 Yeast two hybrid [2]
Other proteins [+] 1 Other proteins +
Interacting Target Name B-cell-activating factor (TNFSF13B) Successful Target Interacting Protein Info
UniProt ID
TN13B_HUMAN 
Synonyms ZTNF4; UNQ401/PRO738; Tumor necrosis factor ligand superfamily member 13B; TNFSF20; TNF-and APOL-related leukocyte expressed ligand 1; TNF- and APOL-related leukocyte expressed ligand 1; TALL-1; TALL1; Dendritic cell-derived TNF-like molecule; CD257; BLyS; BAFF; B lymphocyte stimulator; B cell-activating factor
Evidence Score (E-score) 3 Experimental Evidences +
1 Affinity Capture-Western [3]
2 Reconstituted Complex [3]
3 Reconstituted Complex [2]
References  Top
REF 1 The transmembrane activator TACI triggers immunoglobulin class switching by activating B cells through the adaptor MyD88. Nat Immunol. 2010 Sep;11(9):836-45.
REF 2 TACI is a TRAF-interacting receptor for TALL-1, a tumor necrosis factor family member involved in B cell regulation. J Exp Med. 2000 Jul 3;192(1):137-43.
REF 3 Tumor necrosis factor (TNF) receptor superfamily member TACI is a high affinity receptor for TNF family members APRIL and BLyS. J Biol Chem. 2000 Nov 10;275(45):35478-85.

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