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| Target General Information |
Top |
| Target ID |
T98293 |
Target Info
|
| Target Name |
PAK-4 protein kinase (PAK4) |
| Synonyms |
p21-activated kinase 4; Serine/threonine-protein kinase PAK 4; PAK-4; KIAA1142 |
| Target Type |
Clinical trial Target |
| Gene Name |
PAK4 |
| Biochemical Class |
Kinase |
| UniProt ID |
|
| Target Interacting Proteins |
Top |
| Acid anhydride hydrolases |
[+] 1 Acid anhydride hydrolases |
+ |
| Interacting Protein Name |
Cell division control protein 42 homolog (CDC42) |
Interacting Protein |
Interacting Protein Info
|
| UniProt ID |
|
| Synonyms |
CDC42Hs; G25K |
| Evidence Score (E-score) |
3 Experimental Evidences |
+ |
| 1 |
Affinity Capture-MS |
[1] |
| 2 |
Affinity Capture-Western |
[2] |
| 3 |
Affinity Capture-Western |
[3] |
| References |
Top |
| REF 1 |
Large-scale mapping of human protein-protein interactions by mass spectrometry. Mol Syst Biol. 2007;3:89.
|
| REF 2 |
PAK5, a new brain-specific kinase, promotes neurite outgrowth in N1E-115 cells. Mol Cell Biol. 2002 Jan;22(2):567-77.
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| REF 3 |
PAK4 promotes kinase-independent stabilization of RhoU to modulate cell adhesion. J Cell Biol. 2015 Nov 23;211(4):863-79.
|
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