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| Target General Information |
Top |
| Target ID |
T96894 |
Target Info
|
| Target Name |
Leukemia inhibitory factor receptor (LIFR) |
| Synonyms |
LIF-R; LIF receptor; CD118 |
| Target Type |
Clinical trial Target |
| Gene Name |
LIFR |
| Biochemical Class |
Cytokine receptor |
| UniProt ID |
|
| Target Interacting Proteins |
Top |
| Cytokine receptors |
[+] 1 Cytokine receptors |
+ |
| Interacting Target Name |
Ciliary neurotrophic factor receptor alpha (CNTFR) |
Clinical trial Target |
Interacting Protein Info
|
| UniProt ID |
|
| Synonyms |
CNTFR-alpha; CNTFR alpha; CNTF receptor subunit alpha; Ciliary neurotrophic factor receptor subunit alpha |
| Evidence Score (E-score) |
2 Experimental Evidences |
+ |
| 1 |
Affinity Capture-Western |
[1] |
| 2 |
Reconstituted Complex |
[2] |
| References |
Top |
| REF 1 |
Solution structure of the C-terminal domain of the ciliary neurotrophic factor (CNTF) receptor and ligand free associations among components of the CNTF receptor complex. J Biol Chem. 2003 Jun 27;278(26):23285-94.
|
| REF 2 |
Membrane distal cytokine binding domain of LIFR interacts with soluble CNTFR in vitro. FEBS Lett. 2002 Mar 13;514(2-3):214-8.
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