Target Interacting Protein Information

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Target General Information
Target Interacting Proteins
References
Target General Information  Top
Target ID T95553 Target Info
Target Name ADP-ribosylation factor-like protein 2 (ARL2)
Synonyms ARFL2
Target Type Literature-reported Target
Gene Name ARL2
Biochemical Class Small GTPase
UniProt ID
ARL2_HUMAN 
Target Interacting Proteins  Top
Other proteins [+] 3 Other proteins +
Interacting Protein Name ADP-ribosylation factor-like protein 2-binding protein (ARL2BP) Interacting Protein Interacting Protein Info
UniProt ID
AR2BP_HUMAN 
Synonyms BART; BART1; RP66
Evidence Score (E-score) 5 Experimental Evidences +
1 Co-fractionation [1]
2 Reconstituted Complex [2]
3 Yeast two hybrid [3]
4 Yeast two hybrid [4]
5 Yeast two hybrid [5]
Interacting Protein Name Tubulin-specific chaperone D (TBCD) Interacting Protein Interacting Protein Info
UniProt ID
TBCD_HUMAN 
Synonyms SSD.1; tfcD
Evidence Score (E-score) 2 Experimental Evidences +
1 Co-purification [6]
2 Reconstituted Complex [7]
Interacting Protein Name Protein unc-119 homolog A (UNC119) Interacting Protein Interacting Protein Info
UniProt ID
U119A_HUMAN 
Synonyms HRG4; IMD13; POC7; POC7A
Evidence Score (E-score) 2 Experimental Evidences +
1 Affinity Capture-MS [8]
2 Yeast two hybrid [3]
References  Top
REF 1 ARL2 and BART enter mitochondria and bind the adenine nucleotide transporter. Mol Biol Cell. 2002 Jan;13(1):71-83.
REF 2 The ARF-like 2 (ARL2)-binding protein, BART. Purification, cloning, and initial characterization. J Biol Chem. 1999 Sep 24;274(39):27553-61.
REF 3 A proteome-scale map of the human interactome network. Cell. 2014 Nov 20;159(5):1212-1226.
REF 4 Toward an understanding of the protein interaction network of the human liver. Mol Syst Biol. 2011 Oct 11;7:536.
REF 5 Pooled-matrix protein interaction screens using Barcode Fusion Genetics. Mol Syst Biol. 2016 Apr 22;12(4):863.
REF 6 Cytosolic Arl2 is complexed with cofactor D and protein phosphatase 2A. J Biol Chem. 2003 Oct 17;278(42):40829-36.
REF 7 ADP ribosylation factor-like protein 2 (Arl2) regulates the interaction of tubulin-folding cofactor D with native tubulin. J Cell Biol. 2000 May 29;149(5):1087-96.
REF 8 An organelle-specific protein landscape identifies novel diseases and molecular mechanisms. Nat Commun. 2016 May 13;7:11491.

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