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| Target General Information |
Top |
| Target ID |
T93177 |
Target Info
|
| Target Name |
UNR-interacting protein (STRAP) |
| Synonyms |
WD-40 repeat protein PT-WD; UNRIP; MAWD; MAP activator with WD repeats |
| Target Type |
Literature-reported Target |
| Gene Name |
STRAP |
| Biochemical Class |
WD repeat STRAP family |
| UniProt ID |
|
| Target Interacting Proteins |
Top |
| Kinases |
[+] 1 Kinases |
+ |
| Interacting Target Name |
Glycogen synthase kinase-3 beta (GSK-3B) |
Clinical trial Target |
Interacting Protein Info
|
| UniProt ID |
|
| Synonyms |
Serine/threonine-protein kinase GSK3B; GSK-3 beta |
| Evidence Score (E-score) |
2 Experimental Evidences |
+ |
| 1 |
Affinity Capture-MS |
[1] |
| 2 |
Affinity Capture-Western |
[2] |
| Other proteins |
[+] 1 Other proteins |
+ |
| Interacting Target Name |
Survival motor neuron protein (SMN1) |
Successful Target |
Interacting Protein Info
|
| UniProt ID |
|
| Synonyms |
Survival motor neuron protein; SMNT; SMNC; SMN2; SMN; Gemin-1; Component of gems 1 |
| Evidence Score (E-score) |
2 Experimental Evidences |
+ |
| 1 |
Affinity Capture-MS |
[3] |
| 2 |
Affinity Capture-Western |
[4] |
| References |
Top |
| REF 1 |
Large-scale mapping of human protein-protein interactions by mass spectrometry. Mol Syst Biol. 2007;3:89.
|
| REF 2 |
Role of STRAP in regulating GSK3 function and Notch3 stabilization. Cell Cycle. 2011 May 15;10(10):1639-54.
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| REF 3 |
The SMN interactome includes Myb-binding protein 1a. J Proteome Res. 2010 Jan;9(1):556-63.
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| REF 4 |
A novel functional role for MMSET in RNA processing based on the link between the REIIBP isoform and its interaction with the SMN complex. PLoS One. 2014 Jun 12;9(6):e99493.
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