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| Target General Information |
Top |
| Target ID |
T92750 |
Target Info
|
| Target Name |
Complement factor I (CFI) |
| Synonyms |
IF; Complement factor I light chain; C3B/C4B inactivator |
| Target Type |
Literature-reported Target |
| Gene Name |
CFI |
| Biochemical Class |
Peptidase |
| UniProt ID |
|
| Target Interacting Proteins |
Top |
| Other proteins |
[+] 1 Other proteins |
+ |
| Interacting Target Name |
Complement C3 (CO3) |
Successful Target |
Interacting Protein Info
|
| UniProt ID |
|
| Synonyms |
C3; C3 and PZP-like alpha-2-macroglobulin domain-containing protein 1 |
| Evidence Score (E-score) |
2 Experimental Evidences |
+ |
| 1 |
Biochemical Activity |
[1] |
| 2 |
Reconstituted Complex |
[2] |
| References |
Top |
| REF 1 |
Dissection of CR1, factor H, membrane cofactor protein, and factor B binding and functional sites in the third complement component. J Immunol. 1996 Jun 15;156(12):4821-32.
|
| REF 2 |
Interactions between human complement components factor H, factor I and C3b. Biochem J. 1997 Sep 1;326 ( Pt 2):553-61.
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