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| Target General Information |
Top |
| Target ID |
T92424 |
Target Info
|
| Target Name |
Integrin alpha-V/beta-5 (ITGAV/B5) |
| Synonyms |
Integrin; Vitronectin receptor |
| Target Type |
Discontinued Target |
| Gene Name |
ITGAV-ITGB5 |
| Biochemical Class |
Integrin |
| UniProt ID |
|
| Target Interacting Proteins |
Top |
| Kinases |
[+] 1 Kinases |
+ |
| Interacting Target Name |
Focal adhesion kinase 1 (FAK) |
Clinical trial Target |
Interacting Protein Info
|
| UniProt ID |
|
| Synonyms |
Protein-tyrosine kinase 2; Protein phosphatase 1 regulatory subunit 71; PPP1R71; pp125FAK; p125FAK; FRNK; Focal adhesion kinase-related nonkinase; FAK1; FADK 1; FADK |
| Evidence Score (E-score) |
3 Experimental Evidences |
+ |
| 1 |
Affinity Capture-Western |
[1] |
| 2 |
Affinity Capture-Western |
[2] |
| 3 |
Reconstituted Complex |
[1] |
| References |
Top |
| REF 1 |
Src-mediated coupling of focal adhesion kinase to integrin alpha(v)beta5 in vascular endothelial growth factor signaling. J Cell Biol. 2002 Apr 1;157(1):149-60.
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| REF 2 |
A role for Mer tyrosine kinase in alphavbeta5 integrin-mediated phagocytosis of apoptotic cells. J Cell Sci. 2005 Feb 1;118(Pt 3):539-53.
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