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| Target General Information |
Top |
| Target ID |
T91959 |
Target Info
|
| Target Name |
NAD-dependent deacetylase sirtuin-3 (SIRT3) |
| Synonyms |
hSIRT3; SIR2L3; SIR2-like protein 3; Regulatory protein SIR2 homolog 3 |
| Target Type |
Literature-reported Target |
| Gene Name |
SIRT3 |
| Biochemical Class |
Sirtuin family. Class I subfamily |
| UniProt ID |
|
| Target Interacting Proteins |
Top |
| Other proteins |
[+] 1 Other proteins |
+ |
| Interacting Target Name |
S-phase kinase-associated protein 2 (SKP2) |
Literature-reported Target |
Interacting Protein Info
|
| UniProt ID |
|
| Synonyms |
Skp2; P45skp2; FBXL1; F-box/LRR-repeat protein 1; F-box protein Skp2; Cyclin-A/CDK2-associated protein p45; Cyclin A/CDK2-associated protein p45; Cyclin A/CDK2-associated p45 |
| Evidence Score (E-score) |
2 Experimental Evidences |
+ |
| 1 |
Affinity Capture-Western |
[1] |
| 2 |
Reconstituted Complex |
[2] |
| References |
Top |
| REF 1 |
SIRT3 functions in the nucleus in the control of stress-related gene expression. Mol Cell Biol. 2012 Dec;32(24):5022-34.
|
| REF 2 |
Acetylation-dependent regulation of Skp2 function. Cell. 2012 Jul 6;150(1):179-93.
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