Target Interacting Protein Information

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Target General Information
Target Interacting Proteins
References
Target General Information  Top
Target ID T90828 Target Info
Target Name Interleukin 5 receptor alpha (IL5RA)
Synonyms Interleukin-5 receptor subunit alpha; IL5R; IL-5RA; IL-5R-alpha; IL-5R subunit alpha; IL-5 receptor subunit alpha; CDw125; CD125
Target Type Successful Target
Gene Name IL5RA
Biochemical Class Cytokine receptor
UniProt ID
IL5RA_HUMAN 
Target Interacting Proteins  Top
Other proteins [+] 1 Other proteins +
Interacting Target Name Interleukin-5 (IL5) Successful Target Interacting Protein Info
UniProt ID
IL5_HUMAN 
Synonyms TRF protein; T-cell replacing factor; IL-5; Eosinophil differentiation factor; B-cell differentiation factor I; B cell differentiation factor I
Evidence Score (E-score) 2 Experimental Evidences +
1 Co-fractionation [1]
2 Reconstituted Complex [2]
References  Top
REF 1 Binding interactions of human interleukin 5 with its receptor alpha subunit. Large scale production, structural, and functional studies of Drosophila-expressed recombinant proteins. J Biol Chem. 1995 Apr 21;270(16):9459-71.
REF 2 Three residues in the common beta chain of the human GM-CSF, IL-3 and IL-5 receptors are essential for GM-CSF and IL-5 but not IL-3 high affinity b... EMBO J. 1994 Nov 1;13(21):5176-85.

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