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| Target General Information |
Top |
| Target ID |
T87930 |
Target Info
|
| Target Name |
Glutamate receptor ionotropic kainate 5 (GRIK5) |
| Synonyms |
KA2; Glutamate receptor ionotropic, kainate 5; Glutamate receptor KA-2; GluK5; GRIK2; Excitatory amino acid receptor 2; EAA2 |
| Target Type |
Literature-reported Target |
| Gene Name |
GRIK5 |
| Biochemical Class |
Glutamate-gated ion channel |
| UniProt ID |
|
| Target Interacting Proteins |
Top |
| Microtubule-associated |
[+] 1 Microtubule-associated |
+ |
| Interacting Target Name |
Presynaptic density protein 95 (DLG4) |
Clinical trial Target |
Interacting Protein Info
|
| UniProt ID |
|
| Synonyms |
Synapse-associated protein 90; SAP-90; SAP90; PSD-95; PSD95; Postsynaptic density-95; Postsynaptic density protein 95; Disks large homolog 4; Discs, large homolog 4 |
| Evidence Score (E-score) |
3 Experimental Evidences |
+ |
| 1 |
Affinity Capture-Western |
[1] |
| 2 |
Affinity Capture-Western |
[2] |
| 3 |
Reconstituted Complex |
[2] |
| References |
Top |
| REF 1 |
Molecular mechanisms regulating the differential association of kainate receptor subunits with SAP90/PSD-95 and SAP97. J Biol Chem. 2001 May 11;276(19):16092-9.
|
| REF 2 |
SAP90 binds and clusters kainate receptors causing incomplete desensitization. Neuron. 1998 Oct;21(4):727-39.
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