Target Interacting Protein Information

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Target General Information
Target Interacting Proteins
References
Target General Information  Top
Target ID T85540 Target Info
Target Name Lysine-specific demethylase 5C (KDM5C)
Synonyms XE169; SMCX; Protein Xe169; Protein SmcX; Jumonji/ARID domain-containing protein 1C; JARID1C; Histone demethylase JARID1C; DXS1272E
Target Type Literature-reported Target
Gene Name KDM5C
Biochemical Class Paired donor oxygen oxidoreductase
UniProt ID
KDM5C_HUMAN 
Target Interacting Proteins  Top
Histones [+] 1 Histones +
Interacting Protein Name Histone H3.2 (H32) Interacting Protein Interacting Protein Info
UniProt ID
H32_HUMAN 
Synonyms H3/n; H3/o
Evidence Score (E-score) 3 Experimental Evidences +
1 Biochemical Activity [1]
2 Reconstituted Complex [2]
3 Reconstituted Complex [3]
Transcription regulators [+] 2 Transcription regulators +
Interacting Protein Name Transcription factor E2F6 (E2F6) Interacting Protein Interacting Protein Info
UniProt ID
E2F6_HUMAN 
Synonyms E2F.6
Evidence Score (E-score) 2 Experimental Evidences +
1 Affinity Capture-MS [1]
2 Affinity Capture-MS [4]
Interacting Protein Name Protein max (MAX) Interacting Protein Interacting Protein Info
UniProt ID
MAX_HUMAN 
Synonyms bHLHd4
Evidence Score (E-score) 2 Experimental Evidences +
1 Affinity Capture-MS [1]
2 Affinity Capture-MS [4]
References  Top
REF 1 The histone H3K4 demethylase SMCX links REST target genes to X-linked mental retardation. Nature. 2007 May 31;447(7144):601-5.
REF 2 RBP2 belongs to a family of demethylases, specific for tri-and dimethylated lysine 4 on histone 3. Cell. 2007 Mar 23;128(6):1063-76.
REF 3 The X-linked mental retardation gene SMCX/JARID1C defines a family of histone H3 lysine 4 demethylases. Cell. 2007 Mar 23;128(6):1077-88.
REF 4 A human interactome in three quantitative dimensions organized by stoichiometries and abundances. Cell. 2015 Oct 22;163(3):712-23.

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