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| Target General Information |
Top |
| Target ID |
T83813 |
Target Info
|
| Target Name |
5-HT 2C receptor (HTR2C) |
| Synonyms |
Serotonin receptor 2C; HTR1C; 5HT-1C; 5-hydroxytryptamine receptor 2C; 5-hydroxytryptamine receptor 1C; 5-HTR2C; 5-HT2C receptor; 5-HT2C; 5-HT1C; 5-HT-2C; 5-HT-1C |
| Target Type |
Successful Target |
| Gene Name |
HTR2C |
| Biochemical Class |
GPCR rhodopsin |
| UniProt ID |
|
| Target Interacting Proteins |
Top |
| Other proteins |
[+] 1 Other proteins |
+ |
| Interacting Protein Name |
Multiple PDZ domain protein (MPDZ) |
Interacting Protein |
Interacting Protein Info
|
| UniProt ID |
|
| Synonyms |
HYC2; MUPP1 |
| Evidence Score (E-score) |
5 Experimental Evidences |
+ |
| 1 |
Affinity Capture-Western |
[1] |
| 2 |
Reconstituted Complex |
[1] |
| 3 |
Reconstituted Complex |
[2] |
| 4 |
Yeast two hybrid |
[1] |
| 5 |
Yeast two hybrid |
[3] |
| References |
Top |
| REF 1 |
Interaction of serotonin 5-hydroxytryptamine type 2C receptors with PDZ10 of the multi-PDZ domain protein MUPP1. J Biol Chem. 2001 Apr 20;276(16):12974-82.
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| REF 2 |
Agonist-induced phosphorylation of the serotonin 5-HT2C receptor regulates its interaction with multiple PDZ protein 1. J Biol Chem. 2003 Jun 13;278(24):21576-83.
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| REF 3 |
Cloning and characterization of MUPP1, a novel PDZ domain protein. FEBS Lett. 1998 Mar 6;424(1-2):63-8.
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