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| Target General Information |
Top |
| Target ID |
T82720 |
Target Info
|
| Target Name |
Dual-specificity tyrosine-phosphorylation regulated kinase 1B (DYRK1B) |
| Synonyms |
Minibrain-related kinase; MIRK; Dual specificity tyrosine-phosphorylation-regulated kinase 1B |
| Target Type |
Patented-recorded Target |
| Gene Name |
DYRK1B |
| Biochemical Class |
Kinase |
| UniProt ID |
|
| Target Interacting Proteins |
Top |
| Beta-transducin repeats |
[+] 1 Beta-transducin repeats |
+ |
| Interacting Protein Name |
DDB1- and CUL4-associated factor 7 (DCAF7) |
Interacting Protein |
Interacting Protein Info
|
| UniProt ID |
|
| Synonyms |
AN11; HAN11; SWAN.1; WDR68 |
| Evidence Score (E-score) |
4 Experimental Evidences |
+ |
| 1 |
Affinity Capture-MS |
[1] |
| 2 |
Affinity Capture-Western |
[2] |
| 3 |
Affinity Capture-Western |
[3] |
| 4 |
Co-localization |
[4] |
| References |
Top |
| REF 1 |
The protein interaction landscape of the human CMGC kinase group. Cell Rep. 2013 Apr 25;3(4):1306-20.
|
| REF 2 |
DYRK1A binds to an evolutionarily conserved WD40-repeat protein WDR68 and induces its nuclear translocation. Biochim Biophys Acta. 2011 Oct;1813(10):1728-39.
|
| REF 3 |
The adaptor protein DCAF7 mediates the interaction of the adenovirus E1A oncoprotein with the protein kinases DYRK1A and HIPK2. Sci Rep. 2016 Jun 16;6:28241.
|
| REF 4 |
The WD40-repeat protein Han11 functions as a scaffold protein to control HIPK2 and MEKK1 kinase functions. EMBO J. 2010 Nov 17;29(22):3750-61.
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