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| Target General Information |
Top |
| Target ID |
T82577 |
Target Info
|
| Target Name |
Angiotensin-converting enzyme (ACE) |
| Synonyms |
Kininase II; Dipeptidyl carboxypeptidase I; DCP1; DCP; CD143 antigen; CD143; ACE |
| Target Type |
Successful Target |
| Gene Name |
SLC33A1 |
| Biochemical Class |
Glycosylase |
| UniProt ID |
|
| Target Interacting Proteins |
Top |
| Other proteins |
[+] 1 Other proteins |
+ |
| Interacting Target Name |
Angiotensinogen (AGT) |
Literature-reported Target |
Interacting Protein Info
|
| UniProt ID |
|
| Synonyms |
SERPINA8; Serpin A8 |
| Evidence Score (E-score) |
3 Experimental Evidences |
+ |
| 1 |
Biochemical Activity |
[1] |
| 2 |
Biochemical Activity |
[2] |
| 3 |
Co-crystal Structure |
[3] |
| References |
Top |
| REF 1 |
A novel angiotensin-converting enzyme-related carboxypeptidase (ACE2) converts angiotensin I to angiotensin 1-9. Circ Res. 2000 Sep 1;87(5):E1-9.
|
| REF 2 |
Evaluation of angiotensin-converting enzyme (ACE), its homologue ACE2 and neprilysin in angiotensin peptide metabolism. Biochem J. 2004 Oct 1;383(Pt 1):45-51.
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| REF 3 |
Molecular recognition and regulation of human angiotensin-I converting enzyme (ACE) activity by natural inhibitory peptides. Sci Rep. 2012;2:717.
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