Target Interacting Protein Information

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Target General Information
Target Interacting Proteins
References
Target General Information  Top
Target ID T81135 Target Info
Target Name Skeletal muscle LIM-protein 1 (FHL1)
Synonyms Skeletal muscle LIMprotein 1; SLIM1; SLIM; Four and a half LIM domains protein 1; FHL1
Target Type Literature-reported Target
Gene Name FHL1
UniProt ID
FHL1_HUMAN 
Target Interacting Proteins  Top
Alpha-type channels [+] 1 Alpha-type channels +
Interacting Target Name Voltage-gated potassium channel Kv1.5 (KCNA5) Successful Target Interacting Protein Info
UniProt ID
KCNA5_HUMAN 
Synonyms Voltage-gatedpotassium channel subunit Kv1.5; Voltage-gated potassium channel subunit Kv1.5; Voltage-gated potassium channel HK2; Potassium voltage-gated channel subfamily A member 5; Potassium channel Kv1.5; HPCN1; HK2; 02-Sensitive Potassium Channel Kv1.5
Evidence Score (E-score) 2 Experimental Evidences +
1 Affinity Capture-MS [1]
2 Affinity Capture-Western [2]
Transcription regulators [+] 1 Transcription regulators +
Interacting Target Name Recombining binding protein suppressor of hairless (RBPJ) Literature-reported Target Interacting Protein Info
UniProt ID
SUH_HUMAN 
Synonyms Renal carcinoma antigen NY-REN-30; RBPSUH; RBP-JK; RBPJK; RBP-J kappa; RBP-J; J kappa-recombination signal-binding protein; IGKJRB1; IGKJRB; CBF-1
Evidence Score (E-score) 2 Experimental Evidences +
1 Affinity Capture-MS [3]
2 Affinity Capture-Western [4]
References  Top
REF 1 Four and a half LIM protein 1: a partner for KCNA5 in human atrium. Cardiovasc Res. 2008 Jun 1;78(3):449-57.
REF 2 Four and a half LIM protein 1C (FHL1C): a binding partner for voltage-gated potassium channel K(v1.5). PLoS One. 2011;6(10):e26524.
REF 3 Proteomic analyses reveal distinct chromatin-associated and soluble transcription factor complexes. Mol Syst Biol. 2015 Jan 21;11(1):775.
REF 4 FHL1C induces apoptosis in Notch1-dependent T-ALL cells through an interaction with RBP-J. BMC Cancer. 2014 Jun 22;14:463.

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